{"id":12386,"date":"2022-01-02T09:59:39","date_gmt":"2022-01-02T00:59:39","guid":{"rendered":"https:\/\/www.hoe2021.com\/?p=12386"},"modified":"2022-01-02T20:52:02","modified_gmt":"2022-01-02T11:52:02","slug":"%e3%80%8c%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%ab%e3%82%88%e3%82%8b%e3%82%b9%e3%83%91%e3%82%a4%e3%82%af%e3%82%bf%e3%83%b3%e3%83%91%e3%82%af%e3%81%8cdna%e3%81%ae%e4%bf%ae%e5%be%a9%e3%82%92","status":"publish","type":"post","link":"https:\/\/www.hoe2021.com\/?p=12386","title":{"rendered":"\u300c\u30ef\u30af\u30c1\u30f3\u306b\u3088\u308b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u304cDNA\u306e\u4fee\u5fa9\u3092\u963b\u5bb3\u3059\u308b\u300d\u306f\u30c7\u30de"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 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>PolitiFact\u306e\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hoe2021.com\/?p=12386\/#%E6%87%B8%E5%BF%B5%E3%81%AE%E8%A1%A8%E6%98%8E\" >\u61f8\u5ff5\u306e\u8868\u660e<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hoe2021.com\/?p=12386\/#%E5%8F%82%E8%80%83%E3%81%AB%E3%81%95%E3%81%9B%E3%81%A6%E3%81%84%E3%81%9F%E3%81%A0%E3%81%84%E3%81%9F%E3%83%84%E3%82%A4%E3%83%BC%E3%83%88\" >\u53c2\u8003\u306b\u3055\u305b\u3066\u3044\u305f\u3060\u3044\u305f\u30c4\u30a4\u30fc\u30c8<\/a><\/li><\/ul><\/nav><\/div>\n<h2 id=\"i-0\"><span class=\"ez-toc-section\" id=\"%E3%83%87%E3%83%9E%E3%81%AE%E5%86%85%E5%AE%B9\"><\/span>\u30c7\u30de\u306e\u5185\u5bb9<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<div class=\"say left\">\n<p class=\"faceicon\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/chara\/liar.png\" width=\"110\"><span><\/span><\/p>\n<div class=\"chatting\">\n<div class=\"sc\">\n<p>\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3059\u308b\u3068\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u7d30\u80de\u6838\u306b\u5165\u3063\u3066DNA\u306e\u4fee\u5fa9\u3092\u963b\u5bb3\u3059\u308b\uff01<\/p>\n<p>\u305d\u3046\u3044\u3046\u8ad6\u6587\u304c\u3042\u308b\uff01<\/p>\n<p>\u30ef\u30af\u30c1\u30f3\u5371\u967a\uff01 \u30ef\u30af\u30c1\u30f3\u3084\u3081\u308d\uff01<\/p>\n<\/div>\n<\/div><\/div>\n<p>\u3068\u4e3b\u5f35\u3059\u308b\u4eba\u304c\u3044\u307e\u3059\u304c\u3001\u30c7\u30de\u3067\u3059\u3002<\/p>\n<p>\u66f4\u306b<\/p>\n<div class=\"say left\">\n<p class=\"faceicon\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/chara\/liar.png\" width=\"110\"><span><\/span><\/p>\n<div class=\"chatting\">\n<div class=\"sc\">\n<p>\u3060\u304b\u3089\u764c\u306b\u306a\u308b\uff01<\/p>\n<\/div>\n<\/div><\/div>\n<p>\u3068\u5c3e\u3072\u308c\u3092\u4ed8\u3051\u3066\u3044\u308b\u30c7\u30de\u30c3\u30bf\u30fc\u3082\u3044\u307e\u3059\u304c\u3001\u3082\u3061\u308d\u3093\u6839\u62e0\u306e\u306a\u3044\u30c7\u30de\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u30c7\u30de\u306e\u6839\u62e0\u3068\u3057\u3066\u30c7\u30de\u30c3\u30bf\u30fc\u306b\u60aa\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u4ee5\u4e0b\u306e\u8ad6\u6587\u3067\u3059\u3002<\/p>\n<div class=\"sng-box box2\">\n<p><a href=\"https:\/\/www.mdpi.com\/1999-4915\/13\/10\/2056\" target=\"_blank\" rel=\"noopener\">SARS\u2013CoV\u20132 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro<\/a><\/p>\n<\/div>\n<h2 id=\"i-1\"><span class=\"ez-toc-section\" id=\"%E8%A7%A3%E8%AA%AC\"><\/span>\u89e3\u8aac<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3 id=\"i-2\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E8%AB%96\"><\/span>\u7d50\u8ad6<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u30c7\u30de\u3067\u3059\u3002<\/p>\n<ul>\n<li>\u8ad6\u6587\u306f\u65b0\u578b\u30b3\u30ed\u30ca<strong>\u30a6\u30a4\u30eb\u30b9<\/strong>\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u305f\u3082\u306e\u3067\u3059\u3002\u65b0\u578b\u30b3\u30ed\u30ca<strong>\u30ef\u30af\u30c1\u30f3<\/strong>\u3067\u4f5c\u3089\u308c\u308b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca<strong>\u30a6\u30a4\u30eb\u30b9<\/strong>\u306e\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6539\u826f\u3057\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u3053\u306e\u7814\u7a76\u7d50\u679c\u3092\u305d\u306e\u307e\u307e\u30ef\u30af\u30c1\u30f3\u306b\u3042\u3066\u306f\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/li>\n<li>\u3053\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001\u751f\u304d\u3066\u3044\u308b\u52d5\u7269\u3084\u30d2\u30c8\u306b\u3088\u308b\u8a66\u9a13\u3067\u518d\u73fe\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u81e8\u5e8a\u7684\u304a\u3088\u3073\u751f\u7406\u5b66\u7684\u306a\u59a5\u5f53\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/li>\n<li>\u5b9f\u9a13\u306e\u8a73\u7d30\u306b\u3064\u3044\u3066\u4e0d\u660e\u70b9\u304c\u591a\u3044\u3053\u3068\u3001\u69d8\u3005\u306a\u914d\u616e\u304c\u4e0d\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u306a\u3069\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>2021\u5e7412\u670822\u65e5\u3001\u3053\u306e\u8ad6\u6587\u306b\u5bfe\u3059\u308b\u61f8\u5ff5\u304c\u63d0\u8d77\u3055\u308c\u3001\u8a73\u7d30\u306a\u8abf\u67fb\u304c\u958b\u59cb\u3055\u308c\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n<h3 id=\"i-3\"><span class=\"ez-toc-section\" id=\"PolitiFact%E3%81%AE%E3%83%95%E3%82%A1%E3%82%AF%E3%83%88%E3%83%81%E3%82%A7%E3%83%83%E3%82%AF\"><\/span>PolitiFact\u306e\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u4ee5\u4e0b\u306fPolitiFact\u306e\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af\u8a18\u4e8b\u304b\u3089\u306e\u629c\u7c8b\u3067\u3059\u3002<\/p>\n<blockquote><p><span class=\"haiiro\">An Oct. 13 paper claiming that the spike protein can cause DNA damage has circulated on social media, causing uncertainty about whether these findings are relevant to the COVID-19 vaccines.<\/span><br \/>\n\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304cDNA\u306e\u640d\u50b7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3068\u4e3b\u5f35\u3059\u308b<a href=\"https:\/\/www.mdpi.com\/1999-4915\/13\/10\/2056\" target=\"_blank\" rel=\"noopener\">\uff082021\u5e74\uff0910\u670813\u65e5\u306e\u8ad6\u6587<\/a>\u304c\u30bd\u30fc\u30b7\u30e3\u30eb\u30e1\u30c7\u30a3\u30a2\u4e0a\u3067\u62e1\u6563\u3055\u308c\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u304b\u306e\u3088\u3046\u306a\u5642\u304c\u6d41\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><span class=\"haiiro\">The lab-based context in which the study was conducted, however, limits its relevance to real life conditions outside the lab. And the study\u2019s findings should not be directly translated to the COVID-19 vaccines, which use modified versions of the spike protein.<\/span><br \/>\n\u3057\u304b\u3057\u3001<strong>\u3053\u306e\u7814\u7a76\u306f\u5b9f\u9a13\u5ba4\u306e\u4e2d\u306e\u307f\u3067\u884c\u308f\u308c\u305f<\/strong>\u3082\u306e\u3067\u3042\u308a\u3001\u5b9f\u9a13\u5ba4\u5916\u306e<strong>\u73fe\u5b9f\u4e16\u754c\u306b\u305d\u306e\u307e\u307e\u9069\u7528\u3067\u304d\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093<\/strong>\u3002\u307e\u305f\u3001\u3053\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001<strong>\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6539\u826f\u578b\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3<\/strong>\u306b<strong>\u305d\u306e\u307e\u307e\u53cd\u6620\u3055\u308c\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093<\/strong>\u3002<\/p>\n<p><strong><span class=\"haiiro\">The study in question<\/span><\/strong><br \/>\n<strong>\u554f\u984c\u306e\u7814\u7a76<\/strong><\/p>\n<p><span class=\"haiiro\">Researchers from two Swedish universities introduced into isolated human kidney cells genetic material containing instructions to produce different proteins that make up the COVID-19 virus, including the spike protein. They then examined where these proteins are primarily located in the cell, and tested whether the proteins affected the cell\u2019s DNA damage repair system.<\/span><br \/>\n\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u306e2\u3064\u306e\u5927\u5b66\u306e\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u5206\u96e2\u3057\u305f\u30d2\u30c8\u306e\u814e\u81d3\u7d30\u80de\u306b\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3092\u69cb\u6210\u3059\u308b\u3055\u307e\u3056\u307e\u306a\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u305d\u306e\uff11\u3064\uff09\u306e\u751f\u6210\u3092\u6307\u793a\u3059\u308b\u907a\u4f1d\u7269\u8cea\u3092\u5c0e\u5165\u3057\u307e\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u7d30\u80de\u5185\u306e\u3069\u3053\u306b\u5b58\u5728\u3059\u308b\u304b\u3092\u8abf\u3079\u3001\u305d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u7d30\u80de\u306eDNA\u640d\u50b7\u4fee\u5fa9\u30b7\u30b9\u30c6\u30e0\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u3069\u3046\u304b\u3092\u30c6\u30b9\u30c8\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><span class=\"haiiro\">The researchers found that spike proteins were present in the cell nucleus, the part of the cell that houses DNA. They attributed a reduction in DNA repair efficiency to hindered recruitment of specific proteins involved in the repair process.<\/span><br \/>\n\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001\uff08\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\uff09\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3001\u7d30\u80de\u306e\u6838\uff08DNA\u304c\u3042\u308b\u90e8\u5206\uff09\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u5f7c\u3089\u306f\u3001\u4fee\u5fa9\u30d7\u30ed\u30bb\u30b9\u306b\u95a2\u4e0e\u3059\u308b\u7279\u5b9a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5897\u52a0\u304c\u59a8\u3052\u3089\u308c\u305f\u305f\u3081DNA\u306e\u4fee\u5fa9\u52b9\u7387\u304c\u4f4e\u4e0b\u3057\u305f\u306e\u3060\u3068\u8003\u3048\u307e\u3057\u305f\u3002<\/p>\n<p><span class=\"haiiro\">Their findings differ from&nbsp;previous&nbsp;studies&nbsp;that have found the spike protein to be located primarily outside the nucleus.&nbsp;Studies&nbsp;on the related coronavirus that causes SARS have also found its spike protein to be located in areas outside the nucleus.<\/span><br \/>\n\u4eca\u56de\u306e\u767a\u898b\u306f\u3001\uff08\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\uff09\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4e3b\u306b\u6838\u306e\u5916\u5074\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3068\u306f\u7570\u306a\u308b\u3082\u306e\u3067\u3059\u3002SARS\u306e\u539f\u56e0\u3068\u306a\u308b\u5225\u306e\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306b\u95a2\u3059\u308b\u7814\u7a76\u3067\u3082\u3001\uff08\u30a6\u30a4\u30eb\u30b9\u306e\uff09\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u6838\u306e\u5916\u5074\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><strong><span class=\"haiiro\">Relevance to vaccines<\/span><\/strong><br \/>\n<strong>\u30ef\u30af\u30c1\u30f3\u3068\u306e\u95a2\u9023\u6027<\/strong><\/p>\n<p><span class=\"haiiro\">There are&nbsp;three main types of COVID-19 vaccines&nbsp;that are currently available or being tested in the U.S. Each one involves introducing&nbsp;modified versions of the spike protein&nbsp;to the body in order to prime the immune system to recognize the COVID-19 virus and build defenses against it. This modified version of the spike protein prevents it from assuming the structure that would normally allow it to fuse with the membranes of other cells, unlike the spike protein coded for in the kidney cell study.<\/span><br \/>\n\u73fe\u5728\u3001\u7c73\u56fd\u3067\u5165\u624b\u53ef\u80fd\u307e\u305f\u306f\u8a66\u9a13\u4e2d\u306e\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3068\u3057\u3066\u3001\u4e3b\u306b3\u3064\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002\u3044\u305a\u308c\u3082\u3001\u6539\u5909\u3057\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f53\u5185\u306b\u5c0e\u5165\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u514d\u75ab\u7cfb\u306b\u65b0\u578b\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u3060\u3068\uff08\u8aa4\uff09\u8a8d\u8b58\u3055\u305b\u3001\u305d\u308c\u306b\u5bfe\u3059\u308b\u9632\u5fa1\u3092\u69cb\u7bc9\u3059\u308b\u3088\u3046\u4ed5\u5411\u3051\u308b\u3082\u306e\u3067\u3059\u3002<strong>\u30ef\u30af\u30c1\u30f3\u3067\u7528\u3044\u3089\u308c\u308b\u6539\u826f\u578b\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u814e\u81d3\u7d30\u80de\u306e\u7814\u7a76\u3067\u30b3\u30fc\u30c9\uff08\u751f\u6210\uff09\u3055\u308c\u305f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u306f\u7570\u306a\u308a\u3001\u4ed6\u306e\u7d30\u80de\u819c\u3068\u878d\u5408\u3067\u304d\u306a\u3044\u69cb\u9020\u306b\u306a\u3063\u3066\u3044\u307e\u3059<\/strong>\u3002<\/p>\n<p><span class=\"haiiro\">Unanswered questions also remain.<\/span><br \/>\n\u307e\u305f\u3001\u672a\u89e3\u6c7a\u306e\u554f\u984c\u3082\u6b8b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><span class=\"haiiro\">\u201cThere are a lot of caveats before we can say there is a direct correlation between the vaccines and DNA repair,\u201d said Andre Hudson, head of the Thomas H. Gosnell School of Life Sciences of the Rochester Institute of Technology.<\/span><br \/>\n\u30ed\u30c1\u30a7\u30b9\u30bf\u30fc\u5de5\u79d1\u5927\u5b66\u30c8\u30fc\u30de\u30b9\u30fbH\u30fb\u30b4\u30b9\u30cd\u30eb\u751f\u547d\u79d1\u5b66\u90e8\u9577\u306e\u30a2\u30f3\u30c9\u30ec\u30fb\u30cf\u30c9\u30bd\u30f3\u6c0f\u306f\u3001\u300c\u30ef\u30af\u30c1\u30f3\u3068DNA\u4fee\u5fa9\u306e\u9593\u306b\u76f4\u63a5\u7684\u306a\u76f8\u95a2\u95a2\u4fc2\u304c\u3042\u308b\u3068\u8a00\u3046\u524d\u306b\u3001\u6ce8\u610f\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u70b9\u304c\u3044\u304f\u3064\u3082\u3042\u308a\u307e\u3059\u300d\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><span class=\"haiiro\">One question, for example, is how the genetic material introduced into the kidney cells directed spike protein production: Was it the presence of the spike protein itself, or was it an overabundance of protein that led to their findings?<\/span><br \/>\n\u4f8b\u3048\u3070\u3001\u814e\u81d3\u306e\u7d30\u80de\u306b\u5c0e\u5165\u3055\u308c\u305f\u907a\u4f1d\u7269\u8cea\u304c\u3001\u3069\u306e\u3088\u3046\u306b\u3057\u3066\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u751f\u7523\u3092\u6307\u793a\u3057\u305f\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u767a\u898b\u3055\u308c\u305f\u306e\u306f\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b58\u5728\u305d\u306e\u3082\u306e\u3060\u3063\u305f\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u3001\u904e\u5270\u306b\u767a\u751f\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u3060\u3063\u305f\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n<p><span class=\"haiiro\">Another question is replication: Can these findings be reproduced in other cell types or viruses that also use spike proteins? Does the age of the cells matter? \u201cA lot of experimental details are still needed before you can make a definitive conclusion,\u201d Hudson said.<\/span><br \/>\n\u8907\u88fd\u306b\u3064\u3044\u3066\u3082\u7591\u554f\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001\u4ed6\u306e\u7a2e\u985e\u306e\u7d30\u80de\u3084\u3001\u30b9\u30d1\u30a4\u30af\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f7f\u7528\u3059\u308b\u4ed6\u306e\u30a6\u30a4\u30eb\u30b9\u3067\u3082\u3001\u518d\u73fe\u3067\u304d\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f \u7d30\u80de\u306e\u5e74\u9f62\u306f\u95a2\u4fc2\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u300c<strong>\u5b9f\u9a13\u306e\u8a73\u7d30\u306b\u4e0d\u660e\u306a\u70b9\u304c\u591a\u3044\u305f\u3081\u3001\u65ad\u5b9a\u7684\u306a\u7d50\u8ad6\u3092\u51fa\u3059\u3053\u3068\u306f\u3067\u304d\u306a\u3044<\/strong>\u300d\u3068\u30cf\u30c9\u30bd\u30f3\u7814\u7a76\u54e1\u306f\u8ff0\u3079\u307e\u3057\u305f\u3002<\/p>\n<p><span class=\"haiiro\">The Swedish researchers conducted an&nbsp;in vitro&nbsp;study, meaning it was conducted in a test tube or petri dish in a controlled lab environment. In vitro studies do not necessarily translate directly to what would happen in the much more complex biological environment of the body.<\/span><br \/>\n\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u306e\u7814\u7a76\u8005\u305f\u3061\u304c\u884c\u3063\u305f\u306e\u306f\u3001<a href=\"https:\/\/ja.wikipedia.org\/wiki\/In_vitro\" target=\"_blank\" rel=\"noopener\">in vitro\uff08\u30a4\u30f3\u30fb\u30d3\u30c8\u30ed\uff09<\/a>\u7814\u7a76\u3067\u3059\u3002\u3064\u307e\u308a\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u305f\u7814\u7a76\u5ba4\u306e\u74b0\u5883\u4e0b\u306b\u304a\u3051\u308b\u3001\u8a66\u9a13\u7ba1\u3084\u30b7\u30e3\u30fc\u30ec\u306e\u4e2d\u306e\u7814\u7a76\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002in vitro\uff08\u30a4\u30f3\u30fb\u30d3\u30c8\u30ed\uff09\u7814\u7a76\u3067\u8d77\u304d\u305f\u3053\u3068\u304c\u3001\u3088\u308a\u8907\u96d1\u306a\u751f\u7269\u5b66\u7684\u74b0\u5883\u3067\u3042\u308b\u4f53\u5185\u306b\u304a\u3044\u3066\u540c\u69d8\u306b\u8d77\u304d\u308b\u3068\u306f\u3001\u5fc5\u305a\u3057\u3082\u8a00\u3048\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n<p><span class=\"haiiro\">Unlike the narrower parameters of an in vitro study, there are multiple cell types, immune responses and DNA repair mechanisms at play in people. \u201cThough they may have evidence that it happened in a cell line in an in vitro system, that doesn\u2019t mean that\u2019s the way it would act or behave in animals or people,\u201d said Hudson. \u201cMany studies have been done in vitro that don\u2019t translate to animal model systems.\u201d<\/span><br \/>\n\u8a66\u9a13\u7ba1\u5185\u306e\u7814\u7a76\u306b\u304a\u3051\u308b\u9650\u5b9a\u7684\u306a\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u306f\u7570\u306a\u308a\u3001\u4eba\u9593\u306b\u306f\u8907\u6570\u306e\u7a2e\u985e\u306e\u7d30\u80de\u3001\u8907\u6570\u306e\u514d\u75ab\u53cd\u5fdc\u3001\u8907\u6570\u306eDNA\u4fee\u5fa9\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u300c\u8a66\u9a13\u7ba1\u5185\u306e\u7d30\u80de\u682a\u3067\u8d77\u3053\u3063\u305f\u3068\u3044\u3046\u8a3c\u62e0\u304c\u3042\u3063\u3066\u3082\u3001\u305d\u308c\u304c\u52d5\u7269\u3084\u4eba\u9593\u3067\u3082\u540c\u3058\u3088\u3046\u306b\u4f5c\u7528\u3059\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u300d\u3068\u30cf\u30c9\u30bd\u30f3\u6c0f\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002\u300c\u3053\u308c\u307e\u3067\u8a66\u9a13\u7ba1\u5185\u3067\u884c\u308f\u308c\u305f\u7814\u7a76\u306e\u591a\u304f\u304c\u3001\u52d5\u7269\u30e2\u30c7\u30eb\u7cfb\u3067\u306f\u9069\u7528\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u300d<\/p>\n<p><span class=\"haiiro\">Without replication in a study conducted on live animals or people, this study has limited clinical relevance to the COVID-19 vaccines.<\/span><br \/>\n<strong>\u751f\u304d\u305f\u52d5\u7269\u3084\u4eba\u3092\u5bfe\u8c61\u306b\u3057\u305f\u8a66\u9a13\u3067\u518d\u73fe\u6027\u304c\u78ba\u8a8d\u3055\u308c\u306a\u3044\u9650\u308a<\/strong>\u3001<strong>\u3053\u306e\u7814\u7a76\u7d50\u679c\u3068\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u306e<\/strong>\u81e8\u5e8a\u7684\u306a<strong>\u95a2\u9023\u6027\u306f\u4e4f\u3057\u3044<\/strong>\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n<p><strong><span class=\"haiiro\">Our ruling<\/span><\/strong><br \/>\n<strong>\u7d50\u8ad6<\/strong><\/p>\n<p><span class=\"haiiro\">The study, however, contradicts findings from previous studies that were also conducted on isolated cells in a lab environment. Until their results are replicated in human studies, this has limited bearing on COVID-19 vaccines.<\/span><br \/>\n\u3053\u306e\u7814\u7a76\u7d50\u679c\u306f\u3001\u3053\u308c\u307e\u3067\u306b\u884c\u308f\u308c\u305f\u540c\u69d8\u306e\u7814\u7a76\uff08\u5b9f\u9a13\u5ba4\u306e\u4e2d\u3067\u5206\u96e2\u3055\u308c\u305f\u7d30\u80de\u306b\u5bfe\u3057\u3066\u884c\u308f\u308c\u305f\u7814\u7a76\uff09\u3068\u77db\u76fe\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u304c\u30d2\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u518d\u73fe\u3055\u308c\u308b\u307e\u3067\u306f\u3001\u65b0\u578b\u30b3\u30ed\u30ca\u30ef\u30af\u30c1\u30f3\u3068\u306e\u95a2\u9023\u6027\u306f\u4e4f\u3057\u3044\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.politifact.com\/factchecks\/2021\/nov\/23\/blog-posting\/dna-damage-covid-19-spike-proteins-lab-study-does-\/\" target=\"_blank\" rel=\"noopener\">PolitiFact \u2013 DNA damage from COVID-19 spike proteins in lab study does not apply directly to COVID-19 vaccines<\/a><\/p><\/blockquote>\n<div class=\"memo \">\n<div class=\"memo_ttl dfont\"> \uff08\u53c2\u8003\uff09\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u5f37\u3055<\/div>\n<p><a href=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_4.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-12521\" src=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_4.png\" alt=\"\" width=\"640\" height=\"480\" srcset=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_4.png 640w, https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_4-300x225.png 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\"><\/a><\/p>\n<p>\u8a3c\u62e0\uff08\u79d1\u5b66\u7684\u6839\u62e0\u307e\u305f\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\uff09\u306e\u5f37\u3055\u306f\u3001\u4e0a\u306b\u884c\u304f\u307b\u3069\u5f37\u304f\u306a\u308b\u3002\u4e0a\u306b\u5411\u3051\u3066\u84c4\u7a4d\u3055\u308c\u3066\u3044\u304f\u306e\u3067\u4e8c\u6b21\u7814\u7a76\u304c\u4e00\u6b21\u7814\u7a76\u3092\u62fe\u3044\u304d\u308c\u306a\u3044\u30e9\u30b0\u3082\u8d77\u3053\u308a\u3046\u308b\u3002\u307e\u305f\u52b9\u679c\u306e\u307f\u3092\u8a55\u4fa1\u3057\u526f\u4f5c\u7528\u3092\u8003\u616e\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u3082\u3042\u308b\u3002<\/p>\n<p><a href=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_5.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-12522 bigshadow\" src=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_5.png\" alt=\"\" width=\"339\" height=\"193\" srcset=\"https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_5.png 339w, https:\/\/www.hoe2021.com\/wp-content\/uploads\/2022\/01\/2022-01-02_5-300x171.png 300w\" sizes=\"auto, (max-width: 339px) 100vw, 339px\"><\/a><\/p>\n<p><a href=\"https:\/\/ja.wikipedia.org\/wiki\/In_vitro\" target=\"_blank\" rel=\"noopener\">Wikipedia \u2013 in vitro<\/a><\/p>\n<\/div>\n<h3 id=\"i-4\"><span class=\"ez-toc-section\" id=\"%E6%87%B8%E5%BF%B5%E3%81%AE%E8%A1%A8%E6%98%8E\"><\/span>\u61f8\u5ff5\u306e\u8868\u660e<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\uff12\uff10\uff12\uff11\u5e74\uff11\uff12\u6708\uff12\uff12\u65e5\u3001\u8ad6\u6587\u306b\u5bfe\u3059\u308b\u61f8\u5ff5\u304c\u63d0\u8d77\u3055\u308c\u3001\u8a73\u7d30\u306a\u8abf\u67fb\u304c\u958b\u59cb\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<blockquote><p><span class=\"haiiro\">One of the authors has raised concerns regarding the methodology employed in the study, the conclusions drawn and the insufficient consideration of laboratory staff and resources.<\/span><br \/>\n<span class=\"haiiro\">In order to keep the highest scientific standards, an in-depth investigation is initiated by the responsible editors together with the journal\u2019s editorial office in collaboration with the editorial board, and in accordance with the Committee on Publication Ethics (COPE) guidance. The article will be updated and any necessary corrections made at the conclusion of the investigation process.<\/span><br \/>\n\u8457\u8005\u306e\u4e00\u4eba\u306f\u3001\u3053\u306e\u7814\u7a76\u3067\u63a1\u7528\u3055\u308c\u305f\u65b9\u6cd5\u8ad6\u3001\u5c0e\u304d\u51fa\u3055\u308c\u305f\u7d50\u8ad6\u3001\u7814\u7a76\u6240\u306e\u30b9\u30bf\u30c3\u30d5\u304a\u3088\u3073\u30ea\u30bd\u30fc\u30b9\u3078\u306e\u914d\u616e\u304c\u4e0d\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u306b\u3064\u3044\u3066\u61f8\u5ff5\u3092\u8868\u660e\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u6700\u9ad8\u306e\u79d1\u5b66\u7684\u6c34\u6e96\u3092\u4fdd\u3064\u305f\u3081\u3001\u8cac\u4efb\u7de8\u96c6\u8005\u304c\u7de8\u96c6\u59d4\u54e1\u4f1a\u3068\u5354\u529b\u3057\u3066\u3001\u51fa\u7248\u502b\u7406\u59d4\u54e1\u4f1a\uff08COPE\uff09\u306e\u30ac\u30a4\u30c0\u30f3\u30b9\u306b\u57fa\u3065\u304d\u3001\u30b8\u30e3\u30fc\u30ca\u30eb\u7de8\u96c6\u90e8\u3068\u3068\u3082\u306b\u8a73\u7d30\u306a\u8abf\u67fb\u3092\u958b\u59cb\u3057\u307e\u3059\u3002\u8abf\u67fb\u30d7\u30ed\u30bb\u30b9\u306e\u7d42\u4e86\u5f8c\u3001\u8a18\u4e8b\u306f\u66f4\u65b0\u3055\u308c\u3001\u5fc5\u8981\u306a\u8a02\u6b63\u304c\u884c\u308f\u308c\u307e\u3059\u3002<br \/>\n<a href=\"https:\/\/www.mdpi.com\/1999-4915\/14\/1\/12\/htm\" target=\"_blank\" rel=\"noopener\">Expression of Concern published on 22 December 2021<\/a><\/p><\/blockquote>\n<h2 id=\"i-5\"><span class=\"ez-toc-section\" id=\"%E5%8F%82%E8%80%83%E3%81%AB%E3%81%95%E3%81%9B%E3%81%A6%E3%81%84%E3%81%9F%E3%81%A0%E3%81%84%E3%81%9F%E3%83%84%E3%82%A4%E3%83%BC%E3%83%88\"><\/span>\u53c2\u8003\u306b\u3055\u305b\u3066\u3044\u305f\u3060\u3044\u305f\u30c4\u30a4\u30fc\u30c8<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<blockquote><p>\u6a2a\u304b\u3089\u5931\u793c\u3057\u307e\u3059\u3002\u304a\u305d\u3089\u304fHEK-293cells\u3092\u4f7f\u3063\u305f\u8ad6\u6587\u3067\u3001\u6700\u5f8c\u306b\u3053\u306e\u5b9f\u9a13\u3067\u306f\u4eba\u3001\u52d5\u7269\u3092\u5229\u7528\u305b\u305a\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u57f9\u990a\u3057\u305f\u7d30\u80de\u30ec\u30d9\u30eb\u306e\u8a71\u3067\u3059\u3002\u3053\u306e\u5b9f\u9a13\u3067\u306f,\u4eba\u3067\u540c\u3058\u514d\u75ab\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u793a\u5506\u3057\u3066\u3044\u308b\u7a0b\u5ea6\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002\u8ad6\u6587\u306bcancer\u3068\u8a00\u3046\u5358\u8a9e\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f(\u8ca1\u56e3\u540d\u306e\u307f)<br \/>\n<a href=\"https:\/\/twitter.com\/riho10562636\/status\/1474709711983620098\" target=\"_blank\" rel=\"noopener\">riho nakatani<\/a><\/p><\/blockquote>\n<blockquote><p>\u305d\u3082\u305d\u3082\u3001\u3053\u306e\u8ad6\u6587\u306f\u30ef\u30af\u30c1\u30f3\u306e\u7814\u7a76\u3067\u306f\u306a\u304f\u3001\u611f\u67d3\u306b\u3088\u308b\u30b9\u30d1\u30a4\u30af\u86cb\u767d\u306e\u5f71\u97ff\u3067\u300c\u7d30\u80de\u4fee\u5fa9\u6a5f\u80fd\u3092\u963b\u5bb3\u300d\u304c\u3042\u308b\u3068\u53ef\u80fd\u6027\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3082\u306e\u3067\u3059\u3002\u3060\u304b\u3089\u3001\u30ef\u30af\u30c1\u30f3\u3082\u30b9\u30d1\u30a4\u30af\u86cb\u767d\u304c\u3042\u308b\u306e\u3067\u3088\u308a\u5b89\u5168\u6027\u304c\u9ad8\u3044\u3082\u306e\u3092\u4f5c\u308a\u307e\u3057\u3087\u3046\u3068\u8a00\u3046\u8ad6\u6587\u3067\u3059\u3002\u30ef\u30af\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u30cd\u30ac\u30c6\u30a3\u30d6\u306a\u8ad6\u6587\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br \/>\n<a href=\"https:\/\/twitter.com\/riho10562636\/status\/1475625145142493187\" target=\"_blank\" rel=\"noopener\">riho nakatani<\/a><\/p><\/blockquote>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u691c\u7d22\u30ad\u30fc\u30ef\u30fc\u30c9\uff1a\u6838\u5185\u306b\u5c40\u5728\u3000\u4e3b\u8981\u306aDNA\u4fee\u5fa9\u30bf\u30f3\u30d1\u30af\u8cea\u3000\u640d\u50b7\u90e8\u4f4d\u3078\u306e\u79fb\u52d5\u3092\u59a8\u3052\u3000DNA\u640d\u50b7\u4fee\u5fa9\u3092\u963b\u5bb3\u3000\u6a5f\u80fd\u7684\u306aB\u7d30\u80de\u3084T\u7d30\u80de\u306e\u751f\u7523\u3092\u963b\u5bb3\u3000\u514d\u75ab\u4e0d\u5168\u3000\u514d\u75ab\u7cfb\u306b\u30c0\u30e1\u30fc\u30b8\u3000\u764c\u306e\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u3000\u30a6\u30e1\u30aa\u5927\u5b66\u3000Virus\u8a8c<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30c7\u30de\u306e\u5185\u5bb9 \u3068\u4e3b\u5f35\u3059\u308b\u4eba\u304c\u3044\u307e\u3059\u304c\u3001\u30c7\u30de\u3067\u3059\u3002 \u66f4\u306b \u3068\u5c3e\u3072\u308c\u3092\u4ed8\u3051\u3066\u3044\u308b\u30c7\u30de\u30c3\u30bf\u30fc\u3082\u3044\u307e\u3059\u304c\u3001\u3082\u3061\u308d\u3093\u6839\u62e0\u306e\u306a\u3044\u30c7\u30de\u3067\u3059\u3002 \u3053\u306e\u30c7\u30de\u306e\u6839\u62e0\u3068\u3057\u3066\u30c7\u30de\u30c3\u30bf\u30fc\u306b\u60aa\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u4ee5\u4e0b\u306e\u8ad6\u6587\u3067\u3059\u3002 SARS\u2013CoV\u20132 Sp &#8230; <\/p>\n","protected":false},"author":2,"featured_media":12500,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,5,8],"tags":[],"class_list":{"0":"post-12386","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-covid-19","8":"category-5","9":"category-8","10":"entry"},"_links":{"self":[{"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/posts\/12386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12386"}],"version-history":[{"count":3,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/posts\/12386\/revisions"}],"predecessor-version":[{"id":12523,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/posts\/12386\/revisions\/12523"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=\/wp\/v2\/media\/12500"}],"wp:attachment":[{"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hoe2021.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}